Seventy nine cases of trophoblastic disease were analyzed at the Department of Obstetrics and Gynecology, Chungnam National University from January, 1985 to October, 1989.
The results are as follows：
l. Incidence of trophoblastic disease was one per 31.8 deliveries (3.15％), and it was pathologically consisted with partial mole (27.8％), complete mole (45.6％), invasive mole (17.7％), choriocarcinoma (8.9％)
2. Age group of 26 to 30 was found most frequent (40.5％) and primipara was the most frequent group (43.0％). There was no increase for the persistent disease according to age and para.
3. Clinical manifestations were vaginal bleeding (91.1％), the most common, nausea and vomiting (20.3％), abdominal pain (10.1％) and etc.
4. Molar pregnancies with excessive uterine enlargement were found in 35.6％ and were at increased risk for the persistent disease.
5. Antecedant pregnancies prior to trophoblastic disease where abortion (43.0％), term pregnancy (16.5％) and molar pregnancy (16.5％).
6. β-hCG concentration before November, 1986 was significantly lower than after then. And the first postevacuation β-hCG level was increased in cases of the persistent disease.
7. The treatment regimens in molar pregnancies were suction curettage with prophylactic Act-
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